Endocrine Abstracts

Objectives: To evaluate the different insulin regimens and types of insulin used in our population of type 1 diabetes (DM1) patients in the last revision in our clinic.Method: A descriptive study was carried out in our population of 535 DM1 patients. They had their initial diagnosis between 1967 and 2014.Results: In our population, 47.3% were women and 52.3% were men. The mean age of our patients was 33.8 years (S.D....

Introduction: The European Society of Endocrinology Clinical Practice Guideline defines follow-up recommendations for AI based on the 1 mg overnight dexamethasone suppression test and the presence of associated comorbidities. Follow-up is not recommended for AI presenting serum cortisol levels post dexamethasone ≤1.8 μg/dl neither those presenting serum cortisol levels post dexamethasone between 1.9–5 μg/dl (defined as ‘possible autonomous cortisol se...

Introduction: Episodes of poorly controlled diabetes (DM) are one of the most frequent medical complications during hospitalization in the elderly population.Objectives: To analyze the prevalence of episodes of diabetic decompensation in patients admitted in Orthopedic Surgery and Traumatology (OST) area.Material and methods: Descriptive analysis of patients admitted to OST Service who presented abnormally high or decreased blood g...

Introduction: Episodes of poorly controlled diabetes (DM) are one of the most frequent medical complications during hospitalization in the elderly population.Objetives: To analyze the prevalence of episodes of diabetic decompensation in patients admitted to the area of Vascular Surgery and Angiology (VS).Material and methods: Descriptive analysis of patients admitted to the VS Service who presented abnormally high or decreased bloo...

Pituitary ACTH-secreting tumour presents with variety of clinical features: normal cortisol secretion and ACTH-immunopositive staining and mild hypercortisolism without typical features of Cushing’s disease. We present a 53-year-old male with history of hypertension. First visit (2005): visual loss, bitemporal hemianopsia in campimetry and in MRI pituitary adenoma (2.5 cm) invading cavernous sinus and suprasellar cister. Hormonal study supported panhypopituitarism. After ...

Introduction: Oncocytomas are tumours composed by oncocytes, cells with granular and eosinophilic cytoplasm filled with mitochondria. It is a neoplasm that can arise in several organs (more commonly described in the kidney, salivary gland and thyroid). Oncocytoma arising in the adrenal gland is a rare finding. Most of them are benign and non-functioning and are detected incidentally. However, functional adrenal oncocytomas presenting as Cushing’s syndrome and phaeochromoc...

Introduction: Cushing’s syndrome (CS) due to macronodular adrenal hyperplasia ACTH-independent (MAHAI) is rare. Regulation of cortisol secretion by G-protein-coupled receptors (GPCRs) aberrantly expressed is frequently found in MAHAI. Various aberrant receptors have been reported, mostly: GIP, vasopressin, beta-adrenergic, LH/hCG and serotonin.Case report: 61 years old woman. Medical history: type 2 diabetes, hypertension, obesity, dyslipidaemia and...

Introduction: New long-acting insulin analogues (insulin degludec –ID- and insulin glargine 300 U/ml –IG300-) have proved, in clinical trials, that improve metabolic control with lower hypoglycemia rate in T2D.Objective: To assess characteristics of T2D patients who were given ID and IG300 and to evaluate their effect on metabolic control, weight and insulin dose.Material and methods: We studied T2D patients whose treatme...